WWTR1 Protein (AA 1-400) (His tag)
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- 抗原 See all WWTR1 蛋白
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-400
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This WWTR1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMNPASAP PPLPPPGQQV IHVTQDLDTD LEALFNSVMN PKPSSWRKKI LPESFFKEPD SGSHSRQSST DSSGGHPGPR LAGGAQHVRS HSSPASLQLG TGAGAAGSPA QQHAHLRQQS YDVTDELPLP PGWEMTFTAT GQRYFLNHIE KITTWQDPRK AMNQPLNHMN LHPAVSSTPV PQRSMAVSQP NLVMNHQHQQ QMAPSTLSQQ NHPTQNPPAG LMSMPNALTT QQQQQQKLRL QRIQMERERI RMRQEELMRQ EAALCRQLPM EAETLAPVQA AVNPPTMTPD MRSITNNSSD PFLNGGPYHS REQSTDSGLG LGCYSVPTTP EDFLSNVDEM DTGENAGQTP MNINPQQTRF PDFLDCLPGT NVDLGTLESE DLIPLFNDVE SALNKSEPFL TWL
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product WWTR1 蛋白
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WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 1-400) protein (GST tag)
WWTR1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 201-300) protein (GST tag)WWTR1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 1-400) protein (Strep Tag)Crystallography grade WWTR1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
WW Domain Containing Transcription Regulator 1 (WWTR1) protein (Myc-DYKDDDDK Tag)WWTR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- 别名
- WWTR1 (WWTR1 产品)
- 别名
- WWTR1 Protein, TAZ Protein, 2310058J06Rik Protein, 2610021I22Rik Protein, C78399 Protein, Taz Protein, WW domain containing transcription regulator 1 L homeolog Protein, WW domain containing transcription regulator 1 Protein, wwtr1.L Protein, wwtr1 Protein, WWTR1 Protein, Wwtr1 Protein
- 背景
- WWTR1 is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Recombinant human WWTR1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- 分子量
- 46.5kDa (423aa)
- NCBI登录号
- NP_001161752
- UniProt
- Q9GZV5
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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