Prohibitin 2 Protein (PHB2) (AA 1-299) (His tag)
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- 抗原 See all Prohibitin 2 (PHB2) 蛋白
- Prohibitin 2 (PHB2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-299
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Prohibitin 2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMAQNLKD LAGRLPAGPR GMGTALKLLL GAGAVAYGVR ESVFTVEGGH RAIFFNRIGG VQQDTILAEG LHFRIPWFQY PIIYDIRARP RKISSPTGSK DLQMVNISLR VLSRPNAQEL PSMYQRLGLD YEERVLPSIV NEVLKSVVAK FNASQLITQR AQVSLLIRRE LTERAKDFSL ILDDVAITEL SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PHB2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- Prohibitin 2 (PHB2)
- 别名
- PHB2 (PHB2 产品)
- 别名
- bcap37 Protein, zgc:73150 Protein, wu:fc28c08 Protein, PHB2 Protein, phb2 Protein, ATPHB2 Protein, F21M11.21 Protein, F21M11_21 Protein, prohibitin 2 Protein, DKFZp469N1310 Protein, BAP Protein, BCAP37 Protein, Bap37 Protein, PNAS-141 Protein, REA Protein, p22 Protein, bap37 Protein, prohibitin2 Protein, xphb2 Protein, AU044498 Protein, Bcap37 Protein, Bap Protein, Bap-37 Protein, Bcap27 Protein, prohibitin 2a Protein, prohibitin 2 Protein, prohibitin 2 S homeolog Protein, phb2a Protein, PHB2 Protein, phb2 Protein, phb2.S Protein, Phb2 Protein
- 背景
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. Recombinant human PHB2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 35.7 kDa (322aa)
- NCBI登录号
- NP_001138303
- UniProt
- Q99623
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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