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Prohibitin 2 产品

(Prohibitin 2 (PHB2))
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity).

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Featured Prohibitin 2 Categories

Prohibitin 2 抗体

High quality antibodies with extensive validation data.

Prohibitin 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Prohibitin 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Prohibitin 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (5)
Cat. No. ABIN7269545
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (5)
Cat. No. ABIN2855290
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2783329
Quantity 100 μL
Datasheet Datasheet

Recommended Prohibitin 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1150002
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1150001
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1150003
Quantity 96 tests
Datasheet Datasheet

Recommended Prohibitin 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314865
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1314863
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3131440
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Prohibitin 2 Products

Begum, Lin, Yu, Kim, Yun: "Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity." in: Molecular cancer research : MCR, Vol. 12, Issue 1, pp. 155-64, (2014) (PubMed).

Lacombe, Mangé, Jarlier, Bascoul-Mollevi, Rouanet, Lamy, Maudelonde, Solassol: "Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers." in: International journal of cancer. Journal international du cancer, Vol. 132, Issue 5, pp. 1105-13, (2013) (PubMed).

Liu, Lin, Kang, Huang, Xu, Garcia-Barrio, Olatinwo, Matthews, Chen, Thompson: "Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells." in: PLoS ONE, Vol. 7, Issue 3, pp. e34315, (2012) (PubMed).

Strub, Paillard, Liang, Gomez, Allegood, Hait, Maceyka, Price, Chen, Simpson, Kordula, Milstien, Lesnefsky, Spiegel: "Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 2, pp. 600-12, (2011) (PubMed).

Heidler, Al-Furoukh, Kukat, Salwig, Ingelmann, Seibel, Krüger, Holtz, Wittig, Braun, Szibor: "Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32086-93, (2011) (PubMed).

Zubovych, Straud, Roth: "Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 956-69, (2010) (PubMed).

He, Feng, Mukherjee, Lonard, DeMayo, Katzenellenbogen, Lydon, OMalley: "A repressive role for prohibitin in estrogen signaling." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 2, pp. 344-60, (2008) (PubMed).

Takata, Matsunaga, Morimoto, Ma, Kurihara, Ono-Maniwa, Nakagawa, Azuma, Uchiyama, Fukui: "PHB2 protects sister-chromatid cohesion in mitosis." in: Current biology : CB, Vol. 17, Issue 15, pp. 1356-61, (2007) (PubMed).

Kasashima, Ohta, Kagawa, Endo: "Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2." in: The Journal of biological chemistry, Vol. 281, Issue 47, pp. 36401-10, (2006) (PubMed).

Mishra, Moulik, Murphy: "Prohibitin binds to C3 and enhances complement activation." in: Molecular immunology, Vol. 44, Issue 8, pp. 1897-902, (2006) (PubMed).

Synonyms and alternative names related to Prohibitin 2

prohibitin 2a (phb2a), prohibitin 2 (PHB2), prohibitin 2 (phb2), prohibitin 2 S homeolog (phb2.S), prohibitin 2 (Phb2), ATPHB2, AU044498, BAP, Bap, Bap-37, Bap37, bap37, Bcap27, bcap37, BCAP37, Bcap37, DKFZp469N1310, F21M11.21, F21M11_21, p22, PHB2, phb2, PNAS-141, prohibitin 2, prohibitin2, REA, wu:fc28c08, xphb2, zgc:73150

Protein level used designations for Prohibitin 2

  • B-cell receptor-associated protein 37
  • prohibitin 2
  • Prohibitin-2
  • B-cell associated protein
  • B-cell receptor-associated protein BAP37
  • D-prohibitin
  • prohibitin-2
  • repressor of estrogen receptor activity
  • B-cell receptor associated protein 37
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