Factor VIII Protein (AA 15-629) (His tag)
F8
宿主: Influenza C Virus
宿主: 酵母菌
Recombinant
> 90 %
SDS
1 image
-
- 抗原 See all Factor VIII (F8) 蛋白
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 15-629
-
宿主
- Influenza C Virus
-
资源
- 酵母菌
- 标记
- This Factor VIII protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- EKIKICLQKQ VNSSFSLHNG FGGNLYATEE KRMFELVKPK AGASVLNQST WIGFGDSRTD QSNSAFPRSL MSAKTADKFR SLSGGSLMLS MFGPPGKVDY LYQGCGKHKV FYEGVNWSPH AAIDCYRKNW TDIKLNFQKS IYELASQSHC MSLVNALDKT IPLQVTKGVA KNCNNSFLKN PALYTQEVKP LEQICGEENL AFFTLPTQFG TYECKLHLVA SCYFIYDSKE VYNKRGCGNY FQVIYDSSGK VVGGLDNRVS PYTGNSGDTP TMQCDMLQLK PGRYSVRSSP RFLLMPERSY CFDMKEKGPV TAVQSIWGKG RKSDYAVDQA CLSTPGCMLI QKQKPYIGEA DDHHGDQEMR ELLSGLDYEA RCISQSGWVN ETSPFTEEYL LPPKFGRCPL AAKEESIPKI PDGLLIPTSG TDTTVTKPKS RIFGIDDLII GLLFVAIVEA GIGGYLLGSR KESGGGVTKE SAEKGFEKIG NDIQILRSST NIAIEKLNDR ISHDEQAIRD LTLEIENARS EALLGELGII RALLVGNISI GLQESLWELA SEITNRAGDL AVEVSPGCWI IDNNICDQSC QNFIFKFNET APVPTIPPLD TKIDLQSDPF YWGSS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product F8 蛋白
-
Coagulation Factor VIII (F8) (AA 213-312) protein (GST tag)
F8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Coagulation Factor VIII (F8) (AA 1-216) protein (GST tag)F8 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- 别名
- HEMA (F8 产品)
- 别名
- fb61d02 Protein, wu:fb61d02 Protein, Cf-8 Protein, Cf8 Protein, FVIII Protein, AHF Protein, DXS1253E Protein, F8B Protein, F8C Protein, HEMA Protein, coagulation factor VIIi Protein, coagulation factor VIII Protein, coagulation factor VIII, procoagulant component Protein, f7i Protein, F8 Protein
- 背景
- Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the mbrane of the endocytosed virus particle with the endosomal mbrane. Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase. This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell .
- 分子量
- 70.05 kDa
- UniProt
- P03465
-
You are here:
