电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Factor VIII 产品

(Coagulation Factor VIII (F8))

Categories

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Factor VIII Categories

Factor VIII 抗体

High quality antibodies with extensive validation data.

Factor VIII ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Factor VIII 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Factor VIII 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438070
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434263
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434266
Quantity 100 μL
Datasheet Datasheet

Recommended Factor VIII ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963573
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965897
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954876
Quantity 96 tests
Datasheet Datasheet

Recommended Factor VIII 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353327
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353326
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3079930
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Factor VIII Products

Li, Wen, Su, Yang, Han, Fan: "Local suture ligation-assisted percutaneous sclerotherapy for Kasabach-Merritt phenomenon-associated kaposiform haemangioendothelioma." in: Oncology letters, Vol. 17, Issue 1, pp. 981-989, (2019) (PubMed).

Hu, Wang, Leng, Hu, Shen, Song: "Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells." in: Molecular vision, Vol. 23, pp. 579-587, (2018) (PubMed).

Li, Zhang, Cao, Li, Ye, Shi, Wang, Sun, Wang, Jia, Wang: "Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1847-1854, (2018) (PubMed).

Song, Li, Yu: "Effects of preserving different veins on flow-through flap survival: An experimental study." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 318-324, (2016) (PubMed).

Lei, Peng, Samuel, Zhang, Wu, Wang, Li, Liu: "A simple and biosafe method for isolation of human umbilical vein endothelial cells." in: Analytical biochemistry, Vol. 508, pp. 15-8, (2016) (PubMed).

Kyostio-Moore, Berthelette, Piraino, Sookdeo, Nambiar, Jackson, Burnham, ORiordan, Cheng, Armentano: "The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo." in: Molecular therapy. Methods & clinical development, Vol. 3, pp. 16006, (2016) (PubMed).

Zhu, Hua, Zhu, Li, Wang, Yu, Li: "Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135866, (2016) (PubMed).

Periayah, Halim, Mat Saad, Yaacob, Hussein, Abdul Karim, Abdul Rashid, Ujang: "Effect of the Novel Biodegradable N, O-Carboxymethylchitosan and Oligo-Chitosan on the Platelet Thrombogenicity Cascade in von Willebrand Disease." in: Thrombosis research, Vol. 136, Issue 3, pp. 625-33, (2015) (PubMed).

Li, Cao, Zeng, Liang, Xue, Xi, Zhou, Jiang: "Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-?B pathways." in: Scientific reports, Vol. 5, pp. 8209, (2015) (PubMed).

Zhang, Shen: "A ferulic acid (FA)-eluting system for biodegradable magnesium stent: Cells response of HUVECs." in: Journal of biomedical materials research. Part A, Vol. 103, Issue 8, pp. 2758-69, (2015) (PubMed).

Synonyms and alternative names related to Factor VIII

coagulation factor VIIi (f7i), coagulation factor VIII (F8), coagulation factor VIII, procoagulant component (F8), AHF, Cf-8, Cf8, DXS1253E, F8B, F8C, fb61d02, FVIII, HEMA, wu:fb61d02

Protein level used designations for Factor VIII

  • Factor VIII
  • procoagulant component
  • antihemophilic factor
  • coagulation factor VIII
  • coagulation factor VIIIc
  • factor VIII F8B
  • coagulation factor VIII, procoagulant component (hemophilia A)
  • factor VIII
  • coagulation co-factor
You are here:
客服