Factor VII 产品
(Coagulation Factor VII (F7))
Categories
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
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Featured Factor VII Categories
Factor VII 抗体
High quality antibodies with extensive validation data.
Factor VII ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Factor VII 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Factor VII 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7440011
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN515448
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (3)
Cat. No.
ABIN515449
Quantity
100 μg
Datasheet
Datasheet
Recommended Factor VII ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6574291
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN6574292
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963490
Quantity
96 tests
Datasheet
Datasheet
Recommended Factor VII 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353322
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353324
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3079926
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Factor VII Products
: "Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon)." in: Memórias do Instituto Oswaldo Cruz, Vol. 115, pp. e190364, (2020) (PubMed).: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." in: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).
: "Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity." in: Cardiovascular research, Vol. 114, Issue 8, pp. 1178-1188, (2018) (PubMed).
: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." in: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).
: "TRUST trial: BAY 86-6150 use in haemophilia with inhibitors and assessment for immunogenicity." in: Haemophilia : the official journal of the World Federation of Hemophilia, Vol. 22, Issue 6, pp. 873-879, (2016) (PubMed).
: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." in: British journal of haematology, (2016) (PubMed).
: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." in: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).
: "Coagulation factor VII is regulated by androgen receptor in breast cancer." in: Experimental cell research, Vol. 331, Issue 1, pp. 239-50, (2015) (PubMed).
: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).
: "Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region." in: Human molecular genetics, Vol. 11, Issue 7, pp. 723-31, (2002) (PubMed).
Synonyms and alternative names related to Factor VII
coagulation factor VII (F7), coagulation factor VII (f7), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), coagulation factor VII (CpipJ_CPIJ009142), coagulation factor VII (CpipJ_CPIJ010295), coagulation factor VII (CpipJ_CPIJ020127), coagulation factor VII (fa7), coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog (f7.S), AI114908, AI132620, At-3, At3, ATIII, Cf7, F7, f7, FVII, LOC100223776, mfVII, SPCA, wu:fb59f04, zgc:109870Protein level used designations for Factor VII
- coagulation factor VII
- serum prothrombin conversion accelerator
- clotting factor
- FVII coagulation protein
- eptacog alfa
- proconvertin
- anti-thrombin 3
- antithrombin
- antithrombin-III
- serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
- serpin C1
- serpin peptidase inhibitor, clade C, member 1
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