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YBX1 Protein (AA 2-322) (His tag)

YBX1 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
产品编号 ABIN5713952
发货至: 中国
  • 抗原 See all YBX1 蛋白
    YBX1 (Y Box Binding Protein 1 (YBX1))
    蛋白类型
    Recombinant
    产品特性
    AA 2-322
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 4
    • 3
    • 2
    • 1
    • 1
    酵母菌
    标记
    This YBX1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    SSEAETQQPP AAPAAALSAA DTKPGSTGSG AGSGGPGGLT SAAPAGGDKK VIATKVLGTV KWFNVRNGYG FINRNDTKED VFVHQTAIKK NNPRKYLRSV GDGETVEFDV VEGEKGAEAA NVTGPGGVPV QGSKYAADRN HYRRYPRRRG PPRNYQQNYQ NSESGEKNEG SESAPEGQAQ QRRPYRRRRF PPYYMRRPYA RRPQYSNPPV QGEVMEGADN QGAGEQGRPV RQNMYRGYRP RFRRGPPRQR QPREDGNEED KENQGDETQG QQPPQRRYRR NFNYRRRRPE NPKPQDGKET KAADPPAENS SAPEAEQGGA E
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product YBX1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    YBX1 (Y Box Binding Protein 1 (YBX1))
    别名
    YBOX1 (YBX1 产品)
    别名
    BP-8 Protein, CSDA2 Protein, CSDB Protein, DBPB Protein, MDR-NF1 Protein, NSEP-1 Protein, NSEP1 Protein, YB-1 Protein, YB1 Protein, Byb1 Protein, Cbfa Protein, Dbpb Protein, Ef1a Protein, Msy1 Protein, Nsep1 Protein, Yb1 Protein, bp-8 Protein, csda2 Protein, csdb Protein, dbpb Protein, frgy1 Protein, mdr-nf1 Protein, nsep-1 Protein, nsep1 Protein, yb1 Protein, 1700102N10Rik Protein, C79409 Protein, EF1A Protein, MSY1 Protein, dbpB Protein, mYB-1a Protein, nuclease sensitive element binding protein 1 Protein, Y-box binding protein 1 Protein, Y box binding protein 1 Protein, Y-box binding protein 1 S homeolog Protein, nuclease-sensitive element-binding protein 1 Protein, Y box protein 1 Protein, nsep1 Protein, YBX1 Protein, Ybx1 Protein, ybx1.S Protein, LOC479011 Protein
    背景
    Mediates pre-mRNA alternative splicing regulation. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds preferentially to 5'-[CU]CUGCG-3' motif in vitro .The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
    分子量
    37.6 kDa
    UniProt
    P62960
    途径
    Regulation of Muscle Cell Differentiation
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