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- 抗原 See all KDM5A 蛋白
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 437-603
- 宿主
- 人
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资源
- 酵母菌
- 标记
- This KDM5A protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- EYALSGWNLN NMPVLEQSVL AHINVDISGM KVPWLYVGMC FSSFCWHIED HWSYSINYLH WGEPKTWYGV PSHAAEQLEE VMRELAPELF ESQPDLLHQL VTIMNPNVLM EHGVPVYRTN QCAGEFVVTF PRAYHSGFNQ GYNFAEAVNF CTADWLPIGR QCVNHYR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product KDM5A 蛋白
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Lysine (K)-Specific Demethylase 5A (KDM5A) protein (DYKDDDDK Tag)
KDM5A 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 191-290) protein (GST tag)KDM5A 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 437-603) protein (His-SUMO Tag)KDM5A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Lysine (K)-Specific Demethylase 5A (KDM5A) protein (DYKDDDDK Tag)KDM5A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
- 别名
- KDM5A (KDM5A 产品)
- 别名
- Jarid1a Protein, JARID1A Protein, RBBP-2 Protein, RBBP2 Protein, RBP2 Protein, AA409370 Protein, C76986 Protein, Rbbp2 Protein, lysine demethylase 5A Protein, lysine (K)-specific demethylase 5A Protein, Kdm5a Protein, KDM5A Protein
- 背景
- Histone dethylase that specifically dethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not dethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Dethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone dethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 .
- 分子量
- 21.3 kDa
- UniProt
- P29375
- 途径
- Chromatin Binding, Warburg Effect
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