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PRMT1 Protein (AA 1-248, partial) (GST tag)

PRMT1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5712271
发货至: 中国
  • 抗原 See all PRMT1 蛋白
    PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-248, partial
    宿主
    • 10
    • 3
    • 2
    • 1
    资源
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PRMT1 protein is labelled with GST tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MAAAEAANCI MENFVATLAN GMSLQPPLEE VSCGQAESSE KPNAEDMTSK DYYFDSYAHF GIHEEMLKDE VRTLTYRNSM FHNRHLFKDK VVLDVGSGTG ILCMFAAKAG ARKVIGIECS SISDYAVKIV KANKLDHVVT IIKGKVEEVE LPVEKVDIII SEWMGYCLFY ESMLNTVLYA RDKWLAPDGL IFPDRATLYV TAIEDRQYKD YKIHWWENVY GFDMSCIKDV AIKEPLVDVV DPKQLVTN
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product PRMT1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
    别名
    ANM1 (PRMT1 产品)
    别名
    ANM1 Protein, HCP1 Protein, HRMT1L2 Protein, IR1B4 Protein, 6720434D09Rik Protein, AW214366 Protein, Hrmt1l2 Protein, Mrmt1 Protein, 3E10 Protein, anm1 Protein, hcp1 Protein, hrmt1l2 Protein, ir1b4 Protein, prmt1 Protein, prmt1b Protein, xPRMT1b Protein, xprmt1 Protein, xPRMT1 Protein, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A Protein, ATPRMT1A Protein, F6F22.30 Protein, F6F22_30 Protein, protein arginine methyltransferase 1A Protein, DDBDRAFT_0183976 Protein, DDBDRAFT_0235399 Protein, DDB_0183976 Protein, DDB_0235399 Protein, PRMT1 Protein, DKFZp459J1326 Protein, fb39h07 Protein, wu:fb39h07 Protein, zf1 Protein, zgc:66201 Protein, protein arginine methyltransferase 1 Protein, protein arginine N-methyltransferase 1 Protein, protein arginine methyltransferase 1 L homeolog Protein, protein arginine methyltransferase 1 S homeolog Protein, protein arginine methyltransferase 1A Protein, protein arginine N-methyltransferase-1 Protein, protein arginine N-methyltransferase Protein, protein arginine methyltransferase Protein, PRMT1 Protein, Prmt1 Protein, prmt1.L Protein, prmt1.S Protein, PRMT1A Protein, prm-1 Protein, EDI_007800 Protein, Smp_029240.3 Protein, prmt1 Protein
    背景
    Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Methylates FOXO1 and retains it in the nucleus increasing its transcriptional activity
    分子量
    55.4 kDa
    UniProt
    Q99873
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