PRMT1 Protein (AA 1-248, partial) (GST tag)
(2 references)-
- 抗原 See all PRMT1 蛋白
- PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-248, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PRMT1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS), ELISA
- 序列
- MAAAEAANCI MENFVATLAN GMSLQPPLEE VSCGQAESSE KPNAEDMTSK DYYFDSYAHF GIHEEMLKDE VRTLTYRNSM FHNRHLFKDK VVLDVGSGTG ILCMFAAKAG ARKVIGIECS SISDYAVKIV KANKLDHVVT IIKGKVEEVE LPVEKVDIII SEWMGYCLFY ESMLNTVLYA RDKWLAPDGL IFPDRATLYV TAIEDRQYKD YKIHWWENVY GFDMSCIKDV AIKEPLVDVV DPKQLVTN
- 产品特性
- Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Ref.9 Ref.10 Ref.11 Ref.13 Ref.14 Ref.15 Ref.16 Ref.17 Ref.18 Ref.19
- 纯度
- 90 %
- Top Product
- Discover our top product PRMT1 蛋白
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Protein Arginine Methyltransferase 1 (PRMT1) (AA 1-361) protein (His tag)
PRMT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Protein Arginine Methyltransferase 1 (PRMT1) (AA 1-353) (Active) protein (His-MBP)PRMT1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Protein Arginine Methyltransferase 1 (PRMT1) (AA 1-353) (Active) protein (His-MBP)PRMT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Protein Arginine Methyltransferase 1 (PRMT1) (AA 260-361) protein (GST tag)PRMT1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Protein Arginine Methyltransferase 1 (PRMT1) (AA 1-371) protein (Strep Tag)Crystallography grade PRMT1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Protein Arginine Methyltransferase 1 (PRMT1) (AA 1-361) protein (His tag)Crystallography grade PRMT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Protein Arginine Methyltransferase 1 (PRMT1) protein (DYKDDDDK Tag)PRMT1 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
Protein Arginine Methyltransferase 1 (PRMT1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PRMT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Arginine Methyltransferase 1 (PRMT1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PRMT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 6M guanidine hydrochloride, 20mM Tris
- 储存条件
- -20 °C
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: "Genomic organization, physical mapping, and expression analysis of the human protein arginine methyltransferase 1 gene." in: Biochemical and biophysical research communications, Vol. 278, Issue 2, pp. 349-59, (2000) (PubMed).
: "Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2)." in: Genomics, Vol. 48, Issue 3, pp. 330-40, (1998) (PubMed).
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: "Genomic organization, physical mapping, and expression analysis of the human protein arginine methyltransferase 1 gene." in: Biochemical and biophysical research communications, Vol. 278, Issue 2, pp. 349-59, (2000) (PubMed).
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- 抗原
- PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
- 别名
- Protein arginine N-methyltransferase 1 (PRMT1 产品)
- 别名
- ANM1 Protein, HCP1 Protein, HRMT1L2 Protein, IR1B4 Protein, 6720434D09Rik Protein, AW214366 Protein, Hrmt1l2 Protein, Mrmt1 Protein, 3E10 Protein, anm1 Protein, hcp1 Protein, hrmt1l2 Protein, ir1b4 Protein, prmt1 Protein, prmt1b Protein, xPRMT1b Protein, xprmt1 Protein, xPRMT1 Protein, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A Protein, ATPRMT1A Protein, F6F22.30 Protein, F6F22_30 Protein, protein arginine methyltransferase 1A Protein, DDBDRAFT_0183976 Protein, DDBDRAFT_0235399 Protein, DDB_0183976 Protein, DDB_0235399 Protein, PRMT1 Protein, DKFZp459J1326 Protein, fb39h07 Protein, wu:fb39h07 Protein, zf1 Protein, zgc:66201 Protein, protein arginine methyltransferase 1 Protein, protein arginine N-methyltransferase 1 Protein, protein arginine methyltransferase 1 L homeolog Protein, protein arginine methyltransferase 1 S homeolog Protein, protein arginine methyltransferase 1A Protein, protein arginine N-methyltransferase-1 Protein, protein arginine N-methyltransferase Protein, protein arginine methyltransferase Protein, PRMT1 Protein, Prmt1 Protein, prmt1.L Protein, prmt1.S Protein, PRMT1A Protein, prm-1 Protein, EDI_007800 Protein, Smp_029240.3 Protein, prmt1 Protein
- 背景
- Synonyms: Histone-arginine N-methyltransferase PRMT1,Interferon receptor 1-bound protein 4
- 分子量
- 55.4 kD
- UniProt
- Q99873
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