ARHGDIA Protein (AA 2-204) (GST tag)
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- 抗原 See all ARHGDIA 蛋白
- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-204
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ARHGDIA protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- AEQEPTAEQL AQIAAENEED EHSVNYKPPA QKSIQEIQEL DKDDESLRKY KEALLGRVAV SADPNVPNVV VTGLTLVCSS APGPLELDLT GDLESFKKQS FVLKEGVEYR IKISFRVNRE IVSGMKYIQH TYRKGVKIDK TDYMVGSYGP RAEEYEFLTP VEEAPKGMLA RGSYSIKSRF TDDDKTDHLS WEWNLTIKKD WKD
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product ARHGDIA 蛋白
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rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 24-204) protein (His tag)
ARHGDIA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 59-137) protein (GST tag)ARHGDIA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) protein (GST tag)ARHGDIA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 2-204), (full length) protein (GST tag)ARHGDIA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)ARHGDIA 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
- 别名
- GDIR1 (ARHGDIA 产品)
- 别名
- GDIA1 Protein, NPHS8 Protein, RHOGDI Protein, RHOGDI-1 Protein, Bles01 Protein, zgc:55554 Protein, zgc:77681 Protein, wu:fa96g11 Protein, ARHGDIA Protein, NV15502 Protein, 5330430M07Rik Protein, Gdi-1 Protein, Rho-GDI Protein, RhoDGI Protein, RhoGDI-1 Protein, arhgdia Protein, MGC84535 Protein, gdia1 Protein, rhogdi Protein, rhogdi-1 Protein, rhogdi1 Protein, Rho GDP dissociation inhibitor alpha Protein, Rho GDP dissociation inhibitor (GDI) alpha Protein, rho GDP-dissociation inhibitor 2 Protein, Rho GDP dissociation inhibitor (GDI) alpha L homeolog Protein, ARHGDIA Protein, Arhgdia Protein, arhgdia Protein, LOC100120432 Protein, arhgdia.L Protein
- 背景
- Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from th, and the subsequent binding of GTP to th. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting th from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from mbranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SA5A and PLXNB3 that lead to inactivation of RAC1.
- 分子量
- 50.5 kDa
- UniProt
- P52565
- 途径
- Neurotrophin Signaling Pathway
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