ARHGDIA Protein (AA 24-204) (His tag)
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- 抗原 See all ARHGDIA 蛋白
- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-204
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This ARHGDIA protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- ARHGDIA, 24-204aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
- 别名
- ARHGDIA (ARHGDIA 产品)
- 别名
- GDIA1 Protein, NPHS8 Protein, RHOGDI Protein, RHOGDI-1 Protein, Bles01 Protein, zgc:55554 Protein, zgc:77681 Protein, wu:fa96g11 Protein, ARHGDIA Protein, NV15502 Protein, 5330430M07Rik Protein, Gdi-1 Protein, Rho-GDI Protein, RhoDGI Protein, RhoGDI-1 Protein, arhgdia Protein, MGC84535 Protein, gdia1 Protein, rhogdi Protein, rhogdi-1 Protein, rhogdi1 Protein, Rho GDP dissociation inhibitor alpha Protein, Rho GDP dissociation inhibitor (GDI) alpha Protein, rho GDP-dissociation inhibitor 2 Protein, Rho GDP dissociation inhibitor (GDI) alpha L homeolog Protein, ARHGDIA Protein, Arhgdia Protein, arhgdia Protein, LOC100120432 Protein, arhgdia.L Protein
- 背景
- Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins. Recombinant human ARHGDIA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Rho GDP-dissociation inhibitor 1, GDIA1, RHOGDI, RHOGDI-1, Rho-GDI alpha. NCBI no.: NP_004300
- 分子量
- 22.9 kDa (202aa) confirmed by MALDI-TOF
- 途径
- Neurotrophin Signaling Pathway
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