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ALKBH3 Protein (AA 1-170) (His-SUMO Tag)

ALKBH3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711658
发货至: 中国
  • 抗原 See all ALKBH3 蛋白
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    蛋白类型
    Recombinant
    产品特性
    AA 1-170
    宿主
    • 4
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ALKBH3 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MEEKRRRARV QGAWAAPVKS QAIAQPATTA KSHLHQKPGQ TWKNKEHHLS DREFVFKEPQ QVVRRAPEPR VIEEGVYEIS LSPTGVSRVC LYPGFVDVKE ADWILEQLCQ DVPWKQRTGI REDSILQLTF KKSAPVSGTA TAPQSCWYER PSPPHIPGPA ILTRTRLWAP
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product ALKBH3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    别名
    ALKB3 (ALKBH3 产品)
    别名
    ABH3 Protein, DEPC-1 Protein, DEPC1 Protein, PCA1 Protein, 1700108H04Rik Protein, 1810020C19Rik Protein, Abh3 Protein, mABH3 Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog Protein, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase Protein, alkbh3.L Protein, ALKBH3 Protein, Alkbh3 Protein
    背景
    Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
    分子量
    35.3 kDa
    UniProt
    Q96Q83
    途径
    DNA Damage Repair
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