SMUG1 Protein (AA 1-177, full length) (His-SUMO Tag)
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- 抗原 See all SMUG1 蛋白
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-177
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SMUG1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MPQAFLLGSI HEPAGALMEP QPCPGSLAES FLEEELRLNA ELSQLQFSEP VGIIYNPVEY AWEPHRNYVT RYCQGPKEVL FLGMNPGPFG MAQTGVPFGE VSMVRDWLGI VGPVLTPPQE HPKRPVLGLE CPQSEGPRQS MGHEIKSELL MGGCSWIRGK IQCDRVQVRR PGFSSQL
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SMUG1 蛋白
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Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-177) protein (GST tag)
SMUG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 2-78) protein (GST tag)SMUG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) protein (Myc-DYKDDDDK Tag)SMUG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
- 别名
- SMUG1 (SMUG1 产品)
- 别名
- SMUG1 Protein, xsmug1 Protein, 1200013B09Rik Protein, A930006H09Rik Protein, C85220 Protein, FDG Protein, HMUDG Protein, UNG3 Protein, single-strand-selective monofunctional uracil-DNA glycosylase 1 Protein, single-strand selective monofunctional uracil DNA glycosylase Protein, single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog Protein, SMUG1 Protein, smug1 Protein, smuG1 Protein, smuG Protein, LOC5577584 Protein, CpipJ_CPIJ002767 Protein, Smug1 Protein, smug1.L Protein
- 背景
- Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
- 分子量
- 35.61 kDa
- UniProt
- Q53HV7
- 途径
- DNA Damage Repair
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