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SMARCA2 Protein (AA 700-1216, partial) (His-SUMO Tag)

SMARCA2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5710378
发货至: 中国
  • 抗原 See all SMARCA2 蛋白
    SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
    蛋白类型
    Recombinant
    产品特性
    partial, AA 700-1216
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This SMARCA2 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    SYYTVAHAIS ERVEKQSALL INGTLKHYQL QGLEWMVSLY NNNLNGILAD EMGLGKTIQT IALITYLMEH KRLNGPYLII VPLSTLSNWT YEFDKWAPSV VKISYKGTPA MRRSLVPQLR SGKFNVLLTT YEYIIKDKHI LAKIRWKYMI VDEGHRMKNH HCKLTQVLNT HYVAPRRILL TGTPLQNKLP ELWALLNFLL PTIFKSCSTF EQWFNAPFAM TGERVDLNEE ETILIIRRLH KVLRPFLLRR LKKEVESQLP EKVEYVIKCD MSALQKILYR HMQAKGILLT DGSEKDKKGK GGAKTLMNTI MQLRKICNHP YMFQHIEESF AEHLGYSNGV INGAELYRAS GKFELLDRIL PKLRATNHRV LLFCQMTSLM TIMEDYFAFR NFLYLRLDGT TKSEDRAALL KKFNEPGSQY FIFLLSTRAG GLGLNLQAAD TVVIFDSDWN PHQDLQAQDR AHRIGQQNEV RVLRLCTVNS VEEKILAAAK YKLNVDQKVI QAGMFDQKSS SHERRAF
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product SMARCA2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
    别名
    SMCA2 (SMARCA2 产品)
    别名
    BAF190 Protein, BRM Protein, NCBRS Protein, SNF2 Protein, SNF2L2 Protein, SNF2LA Protein, SWI2 Protein, Sth1p Protein, hBRM Protein, hSNF2a Protein, brm Protein, 2610209L14Rik Protein, SNF2alpha Protein, Snf2l2 Protein, brahma Protein, psa-4 Protein, wu:fa56c07 Protein, wu:fi27f11 Protein, zgc:66238 Protein, Brahma Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog Protein, SMARCA2 Protein, smarca2.L Protein, Smarca2 Protein, smarca2 Protein
    背景
    Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Belongs to the neural progenitors-specific chromatin rodeling complex (npBAF complex) and the neuron-specific chromatin rodeling complex (nBAF complex). During neural development a switch from a st/progenitor to a postmitotic chromatin rodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural st/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural st cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth .
    分子量
    75.7 kDa
    UniProt
    P51531
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