SMARCA2 Protein (AA 1367-1511) (His tag,DYKDDDDK Tag)
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- 抗原 See all SMARCA2 蛋白
- SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1367-1511
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SMARCA2 protein is labelled with His tag,DYKDDDDK Tag.
- 应用范围
- Binding Studies (Bind), Screening Assay (ScA)
- 产品特性
- The peptide corresponding to amino acids 1367-1511 that contains the bromodomain sequences of SMARCA2 / BRM (accession number NP_003061.3) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 22.96 kDa. It shows binding specificity for acetylated H3K9, H3K14, H3K9/14, H4K8, H4K12, H4K16 and H4K5/8/12/16.
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- Discover our top product SMARCA2 蛋白
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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 659-735) protein (GST tag)
SMARCA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 1-1590) protein (Strep Tag)Crystallography grade SMARCA2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 1-1577) protein (Strep Tag)Crystallography grade SMARCA2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 1367-1511) protein (GST tag)SMARCA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Bind, ScA
SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 700-1216), (partial) protein (His tag)SMARCA2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) (AA 700-1216), (partial) protein (His-SUMO Tag)SMARCA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Recombinant SMARCA2 / BRM (1367-1511) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- 限制
- 仅限研究用
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- 注意事项
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 储存条件
- -80 °C
- 储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- 抗原
- SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
- 别名
- SMARCA2 / BRM (SMARCA2 产品)
- 别名
- BAF190 Protein, BRM Protein, NCBRS Protein, SNF2 Protein, SNF2L2 Protein, SNF2LA Protein, SWI2 Protein, Sth1p Protein, hBRM Protein, hSNF2a Protein, brm Protein, 2610209L14Rik Protein, SNF2alpha Protein, Snf2l2 Protein, brahma Protein, psa-4 Protein, wu:fa56c07 Protein, wu:fi27f11 Protein, zgc:66238 Protein, Brahma Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog Protein, SMARCA2 Protein, smarca2.L Protein, Smarca2 Protein, smarca2 Protein
- 背景
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), also known as BRM, is a member of the SWI/SNF family of proteins and is similar to the Brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA2 contains bromodomains for interaction with other proteins. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR). SMARCA1 belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). SMARCA2 plays a pivotal role in the regulation of the switch in subunit composition of the npBAF and nBAF complexes as cells transition from proliferating neural stem/progenitor cells to post-mitotic neurons during neural development.
- 分子量
- 22.96 kDa
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