SLC27A2
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
抗原
SLC27A2
(Solute Carrier Family 27 (Fatty Acid Transporter), Member 2 (SLC27A2))
vlcs Protein, fatp2 Protein, vlacs Protein, acsvl1 Protein, facvl1 Protein, im:7139614 Protein, slc27a2 Protein, wu:fb99g05 Protein, zgc:112376 Protein, ACSVL1 Protein, FACVL1 Protein, HsT17226 Protein, hFACVL1 Protein, FATP2 Protein, VLCS Protein, Vlac Protein, Vlacs Protein, VLACS Protein, solute carrier family 27 (fatty acid transporter), member 2 L homeolog Protein, solute carrier family 27 member 2 Protein, solute carrier family 27 (fatty acid transporter), member 2a Protein, solute carrier family 27 (fatty acid transporter), member 2 Protein, slc27a2.L Protein, SLC27A2 Protein, slc27a2a Protein, slc27a2 Protein, Slc27a2 Protein
背景
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across mbranes .