PTH1R Protein (AA 37-175, Isoform 2) (His tag)
PTH1R
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
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- 抗原 See all PTH1R 蛋白
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- 蛋白类型
- Recombinant
- 产品特性
- Isoform 2, AA 37-175
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PTH1R protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTPGKKK KGKPGKRKEQ EKKKRRTRSA WLDSGVTGSG LEGDHLSDTS TTSLELDSR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product PTH1R 蛋白
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Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) protein (GST tag)
PTH1R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- 别名
- PTHR (PTH1R 产品)
- 别名
- PFE Protein, PTHR Protein, PTHR1 Protein, PPR Protein, Pthr Protein, Pthr1 Protein, pthr1 Protein, zPTH1R Protein, PTHrel Protein, PTH1 Protein, PTH Protein, parathyroid hormone 1 receptor Protein, parathyroid hormone 1 receptor a Protein, PTH1R Protein, Pth1r Protein, pth1ra Protein
- 背景
- Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows th to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath . Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1.1 Publication
- 分子量
- 19.8 kDa
- UniProt
- P12272
- 途径
- Regulation of Carbohydrate Metabolic Process
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