PTH1R Protein (His tag)
-
- 抗原 See all PTH1R 蛋白
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This PTH1R protein is labelled with His tag.
- 原理
- Recombinant Human PTH1R Protein (Gly49, His Tag)
- 序列
- Tyr23-Met 189
- 产品特性
- Recombinant Human Parathyroid hormone 1 receptor is produced by our Mammalian expression system and the target gene encoding Tyr23-Met189 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PTH1R 蛋白
-
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) protein (GST tag)
PTH1R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- 别名
- PTH1R (PTH1R 产品)
- 别名
- PFE Protein, PTHR Protein, PTHR1 Protein, PPR Protein, Pthr Protein, Pthr1 Protein, pthr1 Protein, zPTH1R Protein, PTHrel Protein, PTH1 Protein, PTH Protein, parathyroid hormone 1 receptor Protein, parathyroid hormone 1 receptor a Protein, PTH1R Protein, Pth1r Protein, pth1ra Protein
- 背景
-
Background: Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding, osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand), which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
Synonym: Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor,PTH1R
- 分子量
- 20.2 kDa
- UniProt
- Q0VGD7
- 途径
- Regulation of Carbohydrate Metabolic Process
-
