CTCFL Protein (AA 1-636, full length) (His-SUMO Tag)
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- 抗原 See all CTCFL 蛋白
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-636, full length
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CTCFL protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MAAAEVPVPS GYFTQIKEQK LKPGDLEEEK EEDGVQRVEA QEGVVKEVEA ENSCLLLEAR APVESDRRIL TLQTVHLESQ DVHLQGLGWL SVPHSEELSG TVPEAEGILQ LPSVLWLDPE PQLSLQHCVT VSIPEELYPP EELQRIHFHL LRENVLMAEE NPELTPDLDE STALKKPEED EKDQLPPQGE TDKREERLLL LEMKPKEGKD DEIVLTISHL SLEEQQDPPA ANQTSVPGAK AAKPKRRRQT KGKPQSFQCD TCPFTSSKLS TFNRHIKIHS NERPHLCHLC LKAFRTVTLL RNHVNTHTGT RPHKCRDCDM AFVTSGELVR HRRYKHTYEK PFKCSLCKYA SVEASKMKRH IRSHTGERPF QCCQCAYASR DSYKLKRHMR THSGEKPYEC PTCHVRFTQS GTMKIHIAQK HGENVPKYEC PHCATIIARK SDLRVHLRNL HSQSPEEMKC RYCPAGFHER YALIQHQRTH KNEKKFKCKQ CDYACKQERC LKAHMRMHTG EKPFSCLACN KHFRQKQLLT VHLRKYHDPN FVPNLHLCLK CDKRFSRWSN LQRHRKKCDP EHETLAPNKD RRPVTRTQAS EGEAGHKEGE PQCPGEQALG HQGEAAGSQS PDHGLTCEII FNMMDK
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CTCFL 蛋白
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CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 19-151) protein (His-IF2DI Tag)
CTCFL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 193-293) protein (GST tag)CTCFL 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-663) protein (Strep Tag)Crystallography grade CTCFL 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636) protein (Strep Tag)Crystallography grade CTCFL 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636), (full length) protein (His tag)CTCFL 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
- 别名
- CTCFL (CTCFL 产品)
- 别名
- BORIS Protein, CT27 Protein, CTCF-T Protein, HMGB1L1 Protein, dJ579F20.2 Protein, CTCFL Protein, Boris Protein, OTTMUSG00000016680 Protein, CCCTC-binding factor like Protein, CCCTC-binding factor (zinc finger protein)-like Protein, CTCFL Protein, Ctcfl Protein
- 背景
- Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites. Ses to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
- 分子量
- 89.06 kDa
- UniProt
- A2APF3
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