VEGFR2/CD309 Protein (AA 20-762) (Fc Tag)
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- 抗原 See all VEGFR2/CD309 (VEGFR2) 蛋白
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 20-762
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This VEGFR2/CD309 protein is labelled with Fc Tag.
- 序列
- AA 20-762
- 产品特性
- This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 110.1 kDa. The protein migrates as 120-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product VEGFR2 蛋白
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VEGF Receptor 2 (VEGFR2) (AA 20-764) protein (His-Avi Tag,Biotin)
VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
VEGF Receptor 2 (VEGFR2) (AA 20-764) protein (His-Avi Tag)VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
VEGF Receptor 2 (VEGFR2) protein (mFc Tag)VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
VEGF Receptor 2 (VEGFR2) (AA 20-764) protein (His tag)VEGFR2 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
VEGF Receptor 2 (VEGFR2) (AA 20-764) protein (mFc Tag,Biotin)VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
VEGF Receptor 2 (VEGFR2) (AA 20-764) (Active) protein (His tag)HPLC verified VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
VEGF Receptor 2 (VEGFR2) (AA 20-762) protein (His tag)VEGFR2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
VEGF Receptor 2 (VEGFR2) (AA 807-1356) (Active) protein (GST tag)VEGFR2 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
VEGF Receptor 2 (VEGFR2) (AA 20-764) (Active) protein (His tag,AVI tag,Biotin)VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
VEGF Receptor 2 (VEGFR2) protein (His tag)VEGFR2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- 别名
- VEGF R2 (VEGFR2 产品)
- 别名
- CD309 Protein, FLK1 Protein, VEGFR Protein, VEGFR2 Protein, 6130401C07 Protein, Flk-1 Protein, Flk1 Protein, Krd-1 Protein, Ly73 Protein, VEGFR-2 Protein, sVEGFR-2 Protein, Vegfr-2 Protein, FLK-1 Protein, flk-1 Protein, vegfr-2 Protein, KDR Protein, FLK/KDR Protein, flk1 Protein, flk1b Protein, kdrb Protein, si:busm1-205d10.1 Protein, si:ch211-254j6.1 Protein, si:ch211-278f21.4 Protein, wu:fc31a09 Protein, fk52c05 Protein, flk Protein, kdr Protein, kdra Protein, vegfr2 Protein, vegfr4 Protein, vegr2 Protein, wu:fk52c05 Protein, kinase insert domain receptor Protein, kinase insert domain protein receptor Protein, vascular endothelial growth factor receptor kdr-like Protein, kinase insert domain receptor (a type III receptor tyrosine kinase) Protein, kinase insert domain receptor like Protein, KDR Protein, Kdr Protein, LOC100136647 Protein, kdr Protein, kdrl Protein
- 背景
- Kinase insert domain receptor (KDR) is also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF.The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.
- 分子量
- 110.1 kDa
- 途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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