LRRC32 Protein (AA 20-627) (Fc Tag)
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- 抗原 See all LRRC32 蛋白
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-627
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LRRC32 protein is labelled with Fc Tag.
- 序列
- AA 20-627
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 92.6 kDa. The protein migrates as 35 kDa and 100-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product LRRC32 蛋白
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Leucine Rich Repeat Containing 32 (LRRC32) protein (Fc Tag)
LRRC32 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Leucine Rich Repeat Containing 32 (LRRC32) proteinLRRC32 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Leucine Rich Repeat Containing 32 (LRRC32) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)LRRC32 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 别名
- LRRC32 (LRRC32 产品)
- 别名
- D11S833E Protein, GARP Protein, AI426318 Protein, D11S833Eh Protein, D7H11S833E Protein, EG434215 Protein, Garp Protein, leucine rich repeat containing 32 Protein, LRRC32 Protein, Lrrc32 Protein
- 背景
- Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
- 分子量
- 92.4 kDa
- NCBI登录号
- NP_005503
- 途径
- Activated T Cell Proliferation
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