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LRRC32 Protein (partial) (Fc Tag)

LRRC32 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN5608431
发货至: 中国
  • 抗原 See all LRRC32 蛋白
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    partial
    宿主
    • 6
    • 2
    • 2
    资源
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This LRRC32 protein is labelled with Fc Tag.
    应用范围
    Western Blotting (WB), ELISA
    序列
    His 20 - Asn 627
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Endotoxin level is less than 1.0 EU per ug by the LAL method.
    Biological Activity Comment

    Measured by its binding ability in a functional ELISA. Immobilized Latent TGFB1, N-His at 5 μg/mL (100 uL/well) can bind Human LRRC32, Fc Tag with a linear range of 0.039-2.5 μg/mL (QC tested).

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    Discover our top product LRRC32 蛋白
  • 应用备注
    This recombinant protein can be used for E, WB.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C,-80 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    LRRC32 (LRRC32 产品)
    别名
    D11S833E Protein, GARP Protein, AI426318 Protein, D11S833Eh Protein, D7H11S833E Protein, EG434215 Protein, Garp Protein, leucine rich repeat containing 32 Protein, LRRC32 Protein, Lrrc32 Protein
    背景
    Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
    分子量
    92.6 kDa
    基因ID
    2615
    途径
    Activated T Cell Proliferation
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