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CD3E & CD3G (AA 23-126) (Active) protein (His tag,Fc Tag,DYKDDDDK Tag)

宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
产品编号 ABIN4949087
发货至: 中国
  • 抗原
    CD3E & CD3G
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-126
    宿主
    • 6
    • 5
    • 3
    • 2
    • 1
    资源
    • 17
    HEK-293 Cells
    标记
    His tag,Fc Tag,DYKDDDDK Tag
    应用范围
    Functional Studies (Func)
    序列
    AA 23-126
    产品特性
    The heterodimer Human CD3 epsilon & CD3 gamma is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus, followed by a polyhistidine tag, and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus, followed by a Flag tag. The predicted N-terminus is Asp 23 (CD3E) & Gln 23 (CD3G). The reducing (R) heterodimer protein migrates as 40-50 kDa due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    CD3E & CD3G
    背景
    T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
    分子量
    39.2 kDa (CD3E) & 38.6 kDa (CD3G)
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