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MPZ Protein (AA 30-153) (His tag)

MPZ 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN4370664
发货至: 中国
  • 抗原 See all MPZ 蛋白
    MPZ (Myelin Protein Zero (MPZ))
    蛋白类型
    Recombinant
    产品特性
    AA 30-153
    宿主
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 8
    • 6
    • 2
    • 1
    • 1
    人细胞
    标记
    This MPZ protein is labelled with His tag.
    原理
    Recombinant Human Myelin Protein P0/MPZ (C-6His)
    序列
    IVVYTDREVH GAVGSRVTLH CSFWSSEWVS DDISFTWRYQ PEGGRDAISI FHYAKGQPYI DEVGTFKERI QWVGDPRWKD GSIVIHNLDY SDNGTFTCDV KNPPDIVGKT SQVTLYVFEK VPTRVDHHHH HH
    产品特性
    Recombinant Human Myelin Protein P0/MPZ is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ile30-Arg153) of Human MPZ fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product MPZ 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    MPZ (Myelin Protein Zero (MPZ))
    别名
    Myelin-protein-P0 (MPZ 产品)
    别名
    CHM Protein, CMT1 Protein, CMT1B Protein, CMT2I Protein, CMT2J Protein, CMT4E Protein, CMTDI3 Protein, CMTDID Protein, DSS Protein, HMSNIB Protein, MPP Protein, P0 Protein, Mpp Protein, P-zero Protein, p0 Protein, sc:d0186 Protein, wu:fc04b11 Protein, wu:fi30g06 Protein, zgc:103775 Protein, myelin protein zero Protein, myelin protein zero S homeolog Protein, MPZ Protein, Mpz Protein, mpz Protein, mpz.S Protein
    Sub Type
    Fusionprotein
    背景
    Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.
    Alternative Names: Myelin Protein P0, Myelin Peripheral Protein, MPP, Myelin Protein Zero, MPZ
    分子量
    15.2 kDa
    UniProt
    P25189
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