MASP1 Protein (AA 20-728) (His tag)
MASP1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- 抗原 See all MASP1 蛋白
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-728
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宿主
- 人
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资源
- 人细胞
- 标记
- This MASP1 protein is labelled with His tag.
- 原理
- Recombinant Human Mannan-Binding Lectin Serine Protease 1/MASP1 (C-6His)
- 序列
- HTVELNNMFG QIQSPGYPDS YPSDSEVTWN ITVPDGFRIK LYFMHFNLES SYLCEYDYVK VETEDQVLAT FCGRETTDTE QTPGQEVVLS PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN YIGGYYCSCR FGYILHTDNR TCRVECSDNL FTQRTGVITS PDFPNPYPKS SECLYTIELE EGFMVNLQFE DIFDIEDHPE VPCPYDYIKI KVGPKVLGPF CGEKAPEPIS TQSHSVLILF HSDNSGENRG WRLSYRAAGN ECPELQPPVH GKIEPSQAKY FFKDQVLVSC DTGYKVLKDN VEMDTFQIEC LKDGTWSNKI PTCKIVDCRA PGELEHGLIT FSTRNNLTTY KSEIKYSCQE PYYKMLNNNT GIYTCSAQGV WMNKVLGRSL PTCLPECGQP SRSLPSLVKR IIGGRNAEPG LFPWQALIVV EDTSRVPNDK WFGSGALLSA SWILTAAHVL RSQRRDTTVI PVSKEHVTVY LGLHDVRDKS GAVNSSAARV VLHPDFNIQN YNHDIALVQL QEPVPLGPHV MPVCLPRLEP EGPAPHMLGL VAGWGISNPN VTVDEIISSG TRTLSDVLQY VKLPVVPHAE CKTSYESRSG NYSVTENMFC AGYYEGGKDT CLGDSGGAFV IFDDLSQRWV VQGLVSWGGP EECGSKQVYG VYTKVSNYVD WVWEQMGLPQ SVVEPQVERV DHHHHHH
- 产品特性
- Recombinant Human Mannan-Binding Lectin Serine Protease 1/MASP1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (His20-Arg728) of Human MASP1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product MASP1 蛋白
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Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) protein (GST tag)
MASP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,10 % Glycerol, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- 别名
- MASP1 (MASP1 产品)
- 别名
- AW048060 Protein, CCPII Protein, Crarf Protein, Masp1/3 Protein, 3MC1 Protein, CRARF Protein, CRARF1 Protein, MAP1 Protein, MASP Protein, MASP3 Protein, MAp44 Protein, PRSS5 Protein, RaRF Protein, mannan-binding lectin serine peptidase 1 Protein, mannan binding lectin serine peptidase 1 Protein, Masp1 Protein, MASP1 Protein
- Sub Type
- Fusionprotein
- 背景
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Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
Alternative Names: Mannan-Binding Lectin Serine Protease 1, Complement Factor MASP-3, Complement-Activating Component of Ra-Reactive Factor, Mannose-Binding Lectin-Associated Serine Protease 1, MASP-1, Mannose-Binding Protein-Associated Serine Protease, Ra-Reactive Factor S - 分子量
- 80.68 kDa
- UniProt
- P48740
- 途径
- Complement System
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