ZBP1 Protein (AA 1-149) (His tag)
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- 抗原 See all ZBP1 蛋白
- ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-149
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ZBP1 protein is labelled with His tag.
- 原理
- Recombinant Human Z-DNA Binding Protein 1/ZBP1 (C-6His)
- 序列
- MAQAPADPGR EGHLEQRILQ VLTEAGSPVK LAQLVKECQA PKRELNQVLY RMKKELKVSL TSPATWCLGG TDPEGEGPAE LALSSPAKRP QQHAATIPET PGPQFSQQRE EDIYRFLKDN GPQRALVIAQ ALGMRTAKDV NRDLYRMKSV DHHHHHH
- 产品特性
- Recombinant Human Z-DNA Binding Protein 1/ZBP1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser149) of Human ZBP1 fused with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ZBP1 蛋白
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Z-DNA Binding Protein 1 (ZBP1) (AA 1-149) protein (GST tag)
ZBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Z-DNA Binding Protein 1 (ZBP1) (AA 2-100) protein (GST tag)ZBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Z-DNA Binding Protein 1 (ZBP1) (AA 1-429) protein (Strep Tag)Crystallography grade ZBP1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Z-DNA Binding Protein 1 (ZBP1) (Transcript Variant 1) protein (His tag)ZBP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
- 别名
- ZBP1 (ZBP1 产品)
- 别名
- C20orf183 Protein, DAI Protein, DLM-1 Protein, DLM1 Protein, 2010010H03Rik Protein, Dai Protein, Dlm1 Protein, mZaDLM Protein, ZBP1 Protein, Z-DNA binding protein 1 Protein, ZBP1 Protein, Zbp1 Protein
- Sub Type
- Fusionprotein
- 背景
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Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system. It plays a role in host defense against tumors and pathogens. ZBP1 Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.
Alternative Names: Z-DNA-Binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM, ZBP1, C20orf183, DLM1 - 分子量
- 17.5 kDa
- UniProt
- Q9H171
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