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ZBP1 产品

(Z-DNA Binding Protein 1 (ZBP1))
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

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Featured ZBP1 Categories

ZBP1 抗体

High quality antibodies with extensive validation data.

ZBP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ZBP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ZBP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7437785
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN529332
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IP, ICC
Validations
  • (3)
  • (1)
Cat. No. ABIN1169142
Quantity 100 μg
Datasheet Datasheet

Recommended ZBP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Goat
Analytical Method Competition ELISA
Validations
Cat. No. ABIN996856
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN996858
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN780161
Quantity 96 tests
Datasheet Datasheet

Recommended ZBP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325582
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325584
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319187
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ZBP1 Products

Christgen, Zheng, Kesavardhana, Karki, Malireddi, Banoth, Place, Briard, Sharma, Tuladhar, Samir, Burton, Kanneganti: "Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)." in: Frontiers in cellular and infection microbiology, Vol. 10, pp. 237, (2020) (PubMed).

Du, Ge, Jing, Pan: "Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1." in: International immunopharmacology, Vol. 77, pp. 105944, (2019) (PubMed).

Kuriakose, Zheng, Neale, Kanneganti: "IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 4, pp. 1489-1495, (2019) (PubMed).

Kesavardhana, Kuriakose, Guy, Samir, Malireddi, Mishra, Kanneganti: "ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death." in: The Journal of experimental medicine, Vol. 214, Issue 8, pp. 2217-2229, (2017) (PubMed).

Takaoka, Wang, Choi, Yanai, Negishi, Ban, Lu, Miyagishi, Kodama, Honda, Ohba, Taniguchi: "DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response." in: Nature, Vol. 448, Issue 7152, pp. 501-5, (2007) (PubMed).

Cerná, Cuadrado, Jouve, Díaz de la Espina, De la Torre: "Z-DNA, a new in situ marker for transcription." in: European journal of histochemistry : EJH, Vol. 48, Issue 1, pp. 49-56, (2004) (PubMed).

Wang, Hurley, Pytte, Kirn: "Vocal control neuron incorporation decreases with age in the adult zebra finch." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 24, pp. 10864-70, (2002) (PubMed).

Schwartz, Behlke, Lowenhaupt, Heinemann, Rich: "Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins." in: Nature structural biology, Vol. 8, Issue 9, pp. 761-5, (2001) (PubMed).

Fu, Comella, Tognazzi, Brown, Dvorak, Kocher: "Cloning of DLM-1, a novel gene that is up-regulated in activated macrophages, using RNA differential display." in: Gene, Vol. 240, Issue 1, pp. 157-63, (2000) (PubMed).

Synonyms and alternative names related to ZBP1

Z-DNA binding protein 1 (ZBP1), Z-DNA binding protein 1 (Zbp1), 2010010H03Rik, C20orf183, DAI, Dai, DLM-1, DLM1, Dlm1, mZaDLM, ZBP1

Protein level used designations for ZBP1

  • DNA-dependent activator of IFN-regulatory factors
  • DNA-dependent activator of IRFs
  • DNA-dependent activator of interferon regulatory factors
  • Z-DNA-binding protein 1
  • tumor stroma and activated macrophage protein DLM-1
  • Z-DNA binding protein 1
  • DNA-dependent activator of IFN-regulatory factor
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