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CD38 Protein (AA 43-300) (His tag,AVI tag,Biotin)

宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN3137679
发货至: 中国
  • 抗原 See all CD38 蛋白
    CD38
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 43-300
    宿主
    • 24
    • 10
    • 5
    • 3
    • 1
    资源
    • 17
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD38 protein is labelled with His tag,AVI tag,Biotin.
    序列
    AA 43-300
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 32.5 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD38 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    CD38
    Abstract
    CD38 产品
    别名
    T10 Protein, Cd38-rs1 Protein, cd38 Protein, ADPRC 1 Protein, cADPr hydrolase 1 Protein, CD38 molecule Protein, CD38 antigen Protein, CD38 molecule L homeolog Protein, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Protein, CD38 Protein, Cd38 Protein, cd38.L Protein
    背景
    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
    分子量
    32.5 kDa
    NCBI登录号
    NP_001766
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