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CD38 Protein (AA 43-300) (His tag)

宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2180767
发货至: 中国
  • 抗原 See all CD38 蛋白
    CD38
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 43-300
    宿主
    • 24
    • 10
    • 5
    • 3
    • 1
    资源
    • 17
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CD38 protein is labelled with His tag.
    序列
    AA 43-300
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.7 kDa. The protein migrates as 30-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD38 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM MES, 100 mM NaCl, pH 6.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Wang, Chen, Hou, Liu, Zhang, Zhao, Zhang, An, Li, Hou, Huang, Liu, Zhao, Wei: "ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053." in: European journal of nuclear medicine and molecular imaging, Vol. 48, Issue 9, pp. 2749-2760, (2021) (PubMed).

  • 抗原
    CD38
    Abstract
    CD38 产品
    别名
    T10 Protein, Cd38-rs1 Protein, cd38 Protein, ADPRC 1 Protein, cADPr hydrolase 1 Protein, CD38 molecule Protein, CD38 antigen Protein, CD38 molecule L homeolog Protein, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Protein, CD38 Protein, Cd38 Protein, cd38.L Protein
    背景
    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
    分子量
    30.7 kDa
    NCBI登录号
    NP_001766
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