Neuregulin 4 Protein (NRG4) (AA 2-62) (His tag)
-
- 抗原 See all Neuregulin 4 (NRG4) 蛋白
- Neuregulin 4 (NRG4)
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-62
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Neuregulin 4 protein is labelled with His tag.
- 序列
- AA 2-62
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 8.6 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NRG4 蛋白
-
Neuregulin 4 (NRG4) (AA 1-115) protein (GST tag)
NRG4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neuregulin 4 (NRG4) (AA 1-61) protein (His tag)NRG4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Neuregulin 4 (NRG4) (Active) proteinNRG4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Neuregulin 4 (NRG4) (AA 1-115) protein (Strep Tag)Crystallography grade NRG4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Neuregulin 4 (NRG4) (AA 1-115) protein (Strep Tag)Crystallography grade NRG4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Neuregulin 4 (NRG4) (AA 1-61) protein (rho-1D4 tag)Crystallography grade NRG4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Neuregulin 4 (NRG4) (AA 1-61) protein (rho-1D4 tag)Crystallography grade NRG4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
- 抗原
- Neuregulin 4 (NRG4)
- 别名
- Neuregulin-4 (NRG4 产品)
- 别名
- HRG4 Protein, AI552600 Protein, neuregulin 4 Protein, NRG4 Protein, Nrg4 Protein, LOC100347220 Protein
- 背景
- Neuregulin 4 also known as NRG4 is a member of the neuregulin protein family which in humans is encoded by the NRG4 gene. Loss of expression of NRG4 is frequently seen in advanced bladder cancer while increased NRG4 expression correlates to better survival. The neuregulins, including NRG4, activate type-1 growth factor receptors (EGFR) to initiating cell-to-cell signaling through tyrosine phosphorylation. Furthermore, NRG4 is a low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG4 does not bind to the ERBB1, ERBB2 and ERBB3 receptors.
- 分子量
- 8.6 kDa
- UniProt
- Q8WWG1
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-
