JAG2 Protein (AA 1-1054) (Fc Tag)
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- 抗原 See all JAG2 蛋白
- JAG2 (Jagged 2 (JAG2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1054
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This JAG2 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
- 纯度
- >90 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product JAG2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- JAG2 (Jagged 2 (JAG2))
- 别名
- Jagged-2 (JAG2 产品)
- 别名
- D12Ggc2e Protein, Serh Protein, mJagged2-1 Protein, sm Protein, HJ2 Protein, SER2 Protein, jag2 Protein, serB Protein, zgc:152855 Protein, jagged 2 Protein, jagged 2b Protein, JAG2 Protein, jag2 Protein, Jag2 Protein, jag2b Protein
- 背景
- Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
- 分子量
- ~150kDa (SDS-PAGE)
- UniProt
- Q9Y219
- 途径
- Notch Signaling, Sensory Perception of Sound
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