FNDC5 Protein (AA 29-140) (DYKDDDDK Tag)
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- 抗原 See all FNDC5 蛋白
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 29-140
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宿主
- 人, 小鼠
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资源
- CHO Cells
- 标记
- This FNDC5 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人, 小鼠
- 产品特性
- Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG®-tagged at the N-terminus. Irisin has 100 % identity between mouse, rat, monkey and human.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC5 蛋白
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Fibronectin Type III Domain Containing 5 (FNDC5) (AA 1-137) protein (GST tag)
FNDC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 32-143) protein (His-IF2DI Tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 15-127) protein (His tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 14-78) protein (GST tag)FNDC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) protein (His tag)FNDC5 宿主: 人, 小鼠, 大鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 2-137) (Active) protein (His tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 32-143) (Active) protein (His tag)FNDC5 宿主: 人 宿主: HEK-293 Cells > 97 % AcA, CC Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Activates brown adipocyte markers Ucp1 and Cidec in murine subcutaneous adipocytes at 10ng/ml [Lit. 1].
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- 别名
- Irisin (FNDC5 产品)
- 别名
- FRCP2 Protein, irisin Protein, 1500001L03Rik Protein, AI836596 Protein, C87088 Protein, PeP Protein, Pxp Protein, fndc5 Protein, si:dkey-264p5.1 Protein, zgc:158684 Protein, fibronectin type III domain containing 5 Protein, fibronectin type III domain containing 5b Protein, FNDC5 Protein, Fndc5 Protein, fndc5b Protein
- 背景
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
- 分子量
- ~26kDa
- UniProt
- Q8NAU1
- 途径
- Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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