FNDC5 Protein (AA 32-143) (His tag)
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- 抗原 See all FNDC5 蛋白
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- 生物活性
- Active
- 产品特性
- AA 32-143
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FNDC5 protein is labelled with His tag.
- 应用范围
- Activity Assay (AcA), Cell Culture (CC)
- 产品特性
- Tag location: N-terminal His Tag
- 纯度
- > 97 %
- Biological Activity Comment
- The protein encoded by FNDC5 can be cleaved into Irisin, which is a myokine linked to exercise and lean body mass. It was reported that FNDC5 significantly decreased cell number, migration and viability through apoptosis in malignant MDA-MB-231 cells. Thus MDA-MB-231 cells were seeded overnight at a density of 5,000 cells/well, and treated with or without various concentrations of FNDC5 for 48h, then MDA-MB-231 cells were observed by inverted microscope and cell viability was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10μL of CCK-8 solution was added to each well of the plate, then measure the absorbance at 450nm using a microplate reader after incubating the plate for 1-4 hours in at 37oC. Cell apoptosis of MDA-MB-231 cells after incubation with FNDC5 for 48h observed by inverted microscope was shown in Figure 1. .
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- Discover our top product FNDC5 蛋白
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Fibronectin Type III Domain Containing 5 (FNDC5) (AA 1-137) protein (GST tag)
FNDC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 32-143) protein (His-IF2DI Tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 15-127) protein (His tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 14-78) protein (GST tag)FNDC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) protein (His tag)FNDC5 宿主: 人, 小鼠, 大鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 2-137) (Active) protein (His tag)FNDC5 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
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- 应用备注
- Isoelectric Point: 5
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.6, containing 5 % trehalose.
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- 抗原
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- 别名
- Fibronectin Type III Domain Containing Protein 5 (FNDC5) (FNDC5 产品)
- 别名
- FRCP2 Protein, irisin Protein, 1500001L03Rik Protein, AI836596 Protein, C87088 Protein, PeP Protein, Pxp Protein, fndc5 Protein, si:dkey-264p5.1 Protein, zgc:158684 Protein, fibronectin type III domain containing 5 Protein, fibronectin type III domain containing 5b Protein, FNDC5 Protein, Fndc5 Protein, fndc5b Protein
- 背景
- Alternative Names: FRCP2, Irisin, Fibronectin type III repeat-containing protein 2
- 分子量
- 27kDa
- UniProt
- Q8NAU1
- 途径
- Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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