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VRK1 Protein (His tag)

VRK1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735437
发货至: 中国
  • 抗原 See all VRK1 蛋白
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    蛋白类型
    Recombinant
    宿主
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    资源
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    大肠杆菌(E. Coli)
    标记
    This VRK1 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human VRK1 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product VRK1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    别名
    Vrk1 (VRK1 产品)
    别名
    vrk1 Protein, MGC64390 Protein, MGC75762 Protein, VRK1 Protein, PCH1 Protein, PCH1A Protein, 51PK Protein, wu:fe16f06 Protein, zgc:56266 Protein, vaccinia related kinase 1 L homeolog Protein, vaccinia related kinase 1 Protein, Serine/threonine-protein kinase VRK1 Protein, vrk1.L Protein, vrk1 Protein, VRK1 Protein, vrk-1 Protein, Vrk1 Protein
    背景
    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
    分子量
    45.3 kDa
    NCBI登录号
    NP_003375
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