Vinculin Protein (VCL) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)-
- 抗原 See all Vinculin (VCL) 蛋白
- Vinculin (VCL)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Vinculin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Vinculin (VCL) (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VCL 蛋白
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Vinculin (VCL) (AA 2-235) protein (His tag)
VCL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Vinculin (VCL) (AA 777-1066) protein (GST tag)VCL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Vinculin (VCL) (AA 1-1066) protein (GST tag)VCL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vinculin (VCL) protein (His tag)VCL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Vinculin (VCL) (AA 2-1134) protein (His tag)Crystallography grade VCL 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Autoantibodies against vinculin in patients with chronic inflammatory demyelinating polyneuropathy." in: Journal of neuroimmunology, Vol. 287, pp. 9-15, (2015) (PubMed).
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: "Autoantibodies against vinculin in patients with chronic inflammatory demyelinating polyneuropathy." in: Journal of neuroimmunology, Vol. 287, pp. 9-15, (2015) (PubMed).
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- 抗原
- Vinculin (VCL)
- Abstract
- VCL 产品
- 别名
- CMD1W Protein, CMH15 Protein, MV Protein, MVCL Protein, VCL Protein, im:6902790 Protein, hm:zehn2160 Protein, DDBDRAFT_0186762 Protein, DDBDRAFT_0232320 Protein, DDB_0186762 Protein, DDB_0232320 Protein, 9430097D22 Protein, AA571387 Protein, AI462105 Protein, AW545629 Protein, CG3299 Protein, CT11081 Protein, Dmel\\CG3299 Protein, Dmvincp Protein, EG:103B4.1 Protein, Vin Protein, Vin2EF Protein, vinc Protein, LOC100228062 Protein, vcl-A Protein, vinculin Protein, vinculin a Protein, vinculin A Protein, Vinculin Protein, vinculin S homeolog Protein, VCL Protein, vcla Protein, vinA Protein, Vcl Protein, Vinc Protein, CpipJ_CPIJ013873 Protein, Bm1_37935 Protein, vcl Protein, vcl.S Protein
- 背景
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
- 分子量
- 116.5 kDa
- NCBI登录号
- NP_003364
- 途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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