VNN1 Protein (His tag)
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- 抗原 See all VNN1 蛋白
- VNN1 (Vanin 1 (VNN1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VNN1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Vanin-1 / Pantetheinase protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product VNN1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- VNN1 (Vanin 1 (VNN1))
- 别名
- Vanin-1,pantetheinase (VNN1 产品)
- 别名
- HDLCQ8 Protein, Tiff66 Protein, V-1 Protein, hdlcq8 Protein, tiff66 Protein, vnn1.1 Protein, vanin-1 Protein, vanin 1 Protein, pantetheinase Protein, VNN1 Protein, Vnn1 Protein, vnn1 Protein, LOC100217969 Protein
- 背景
- This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
- 分子量
- 53.3 kDa
- NCBI登录号
- NP_004657
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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