VNN1 Protein (AA 24-488) (His tag)
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- 抗原 See all VNN1 蛋白
- VNN1 (Vanin 1 (VNN1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-488
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This VNN1 protein is labelled with His tag.
- 原理
- Mouse VNN1 Protein
- 序列
- Leu24-Asn488
- 产品特性
- Recombinant Mouse VNN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Asn488.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product VNN1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4. Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- VNN1 (Vanin 1 (VNN1))
- 别名
- VNN1 (VNN1 产品)
- 别名
- HDLCQ8 Protein, Tiff66 Protein, V-1 Protein, hdlcq8 Protein, tiff66 Protein, vnn1.1 Protein, vanin-1 Protein, vanin 1 Protein, pantetheinase Protein, VNN1 Protein, Vnn1 Protein, vnn1 Protein, LOC100217969 Protein
- 背景
- Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a blood biomarker for the discrimination of PCAD from type 2 diabetes.
- 分子量
- 53.14 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9Z0K8
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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