UHRF1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all UHRF1 蛋白
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This UHRF1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human UHRF1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UHRF1 蛋白
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Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 96-297) protein (His tag)
UHRF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 694-793) protein (GST tag)UHRF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 1-793) protein (Strep Tag)Crystallography grade UHRF1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- 别名
- Uhrf1 (UHRF1 产品)
- 别名
- ICBP90 Protein, Np95 Protein, RNF106 Protein, hNP95 Protein, hUHRF1 Protein, AL022808 Protein, NP95 Protein, fb97f09 Protein, wu:fb97f09 Protein, zgc:63539 Protein, UHRF1 Protein, ubiquitin like with PHD and ring finger domains 1 Protein, ubiquitin-like, containing PHD and RING finger domains, 1 Protein, ubiquitin-like with PHD and ring finger domains 1 Protein, UHRF1 Protein, Uhrf1 Protein, uhrf1 Protein
- 背景
- This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.
- 分子量
- 90.9 kDa
- NCBI登录号
- NP_037414
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