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STING/TMEM173 Protein (Myc-DYKDDDDK Tag)

TMEM173 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2733879
发货至: 中国
  • 抗原 See all STING/TMEM173 (TMEM173) 蛋白
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 4
    • 2
    资源
    • 8
    • 4
    • 1
    HEK-293 Cells
    标记
    This STING/TMEM173 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human TMEM173 / STING protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TMEM173 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    别名
    Tmem173,sting (TMEM173 产品)
    别名
    ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein
    背景
    This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
    分子量
    42 kDa
    NCBI登录号
    NP_938023
    途径
    Activation of Innate immune Response
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