STING/TMEM173 Protein (Fc Tag)
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- 抗原 See all STING/TMEM173 (TMEM173) 蛋白
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This STING/TMEM173 protein is labelled with Fc Tag.
- 原理
- Recombinant human TMEM173 protein with N-terminal Human Fc tag
- 特异性
- HFc (Glu99-Ala330) TMEM173 (Leu139-Ser379)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TMEM173 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 别名
- TMEM173 (TMEM173 产品)
- 别名
- ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein
- 背景
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Synonymes: ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173
Description: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. - 分子量
- predicted molecular mass of 53.2 kDa after removal of the signal peptide.
- 基因ID
- 340061
- UniProt
- Q86WV6
- 途径
- Activation of Innate immune Response
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