TIRAP Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- 抗原 See all TIRAP 蛋白
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 3
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TIRAP protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human TIRAP (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TIRAP 蛋白
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Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-256) protein (GST tag)
TIRAP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) protein (Strep Tag)Crystallography grade TIRAP 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-241) protein (Strep Tag)Crystallography grade TIRAP 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- 别名
- Tirap (TIRAP 产品)
- 别名
- mal Protein, wyatt Protein, BACTS1 Protein, Mal Protein, MyD88-2 Protein, AA407980 Protein, C130027E04Rik Protein, Tlr4ap Protein, Wyatt Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein Protein, TIR domain containing adaptor protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein Protein, tirap Protein, TIRAP Protein, tirap.L Protein, Tirap Protein
- 背景
- The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants however, not all variants have been fully described.
- 分子量
- 23.7 kDa
- NCBI登录号
- NP_001034750
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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