TAB1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all TAB1 蛋白
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TAB1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human TAB1 / MAP3K7IP1 (transcript variant alpha) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TAB1 蛋白
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TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-200) protein (His tag)
TAB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) protein (GST tag)TAB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 3-100) protein (GST tag)TAB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) protein (His tag)TAB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) protein (Strep Tag)Crystallography grade TAB1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-502) protein (Strep Tag)Crystallography grade TAB1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
- 别名
- Tab1,map3k7ip1 (TAB1 产品)
- 别名
- 3'-Tab1 Protein, MAP3K7IP1 Protein, 2310012M03Rik Protein, Map3k7ip1 Protein, b2b449Clo Protein, TGF-beta activated kinase 1 (MAP3K7) binding protein 1 Protein, TGF-beta activated kinase 1/MAP3K7 binding protein 1 Protein, TAB1 Protein, Tab1 Protein
- 背景
- The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- 分子量
- 54.5 kDa
- NCBI登录号
- NP_006107
- 途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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