STAT5A Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all STAT5A 蛋白
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This STAT5A protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human STAT5 / STAT5A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product STAT5A 蛋白
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Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) protein (GST tag)
STAT5A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) protein (GST tag)STAT5A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-793) protein (Strep Tag)Crystallography grade STAT5A 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) protein (Strep Tag)Crystallography grade STAT5A 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
- 别名
- Stat5,stat5a (STAT5A 产品)
- 别名
- MGF Protein, STAT5 Protein, AA959963 Protein, Stat5 Protein, STAT5A/MGF Protein, STATA5 Protein, STAT5A Protein, stat5 Protein, stat5b Protein, signal transducer and activator of transcription 5A Protein, signal transducer and activator of transcription 5a Protein, STAT5A Protein, Stat5a Protein, stat5a Protein, LOC100348518 Protein, LOC100716811 Protein
- 背景
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.
- 分子量
- 90.5 kDa
- NCBI登录号
- NP_003143
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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