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SLC12A3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SLC12A3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2732145
发货至: 中国
  • 抗原 See all SLC12A3 蛋白
    SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 5
    • 3
    资源
    • 3
    • 3
    • 2
    HEK-293 Cells
    标记
    This SLC12A3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human SLC12A3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SLC12A3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3))
    别名
    Slc12a3 (SLC12A3 产品)
    别名
    SLC12A3 Protein, slc12a3 Protein, DKFZp469N2315 Protein, NCC Protein, NCCT Protein, TSC Protein, AI035291 Protein, solute carrier family 12 member 3 Protein, solute carrier family 12 (sodium/chloride transporter), member 3 Protein, solute carrier family 12, member 3 Protein, SLC12A3 Protein, slc12a3.2 Protein, Slc12a3 Protein
    背景
    This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    113.7 kDa
    NCBI登录号
    NP_000330
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