SIP1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all SIP1 (GEMIN2) 蛋白
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SIP1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human SIP1 / GEMIN2 (transcript variant alpha) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GEMIN2 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- 别名
- Sip1,gemin2 (GEMIN2 产品)
- 别名
- SIP1 Protein, SIP1-delta Protein, 1700012N19Rik Protein, Sip1 Protein, sip1 Protein, sip1-delta Protein, wu:fc52a05 Protein, zgc:110274 Protein, gem nuclear organelle associated protein 2 Protein, gem (nuclear organelle) associated protein 2 Protein, gem nuclear organelle associated protein 2 S homeolog Protein, GEMIN2 Protein, Gemin2 Protein, gemin2.S Protein, gemin2 Protein
- 背景
- This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
- 分子量
- 31.4 kDa
- NCBI登录号
- NP_003607
- 途径
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
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