PPM1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all PPM1A 蛋白
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PPM1A protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Protein phosphatase 1A / PPM1A (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PPM1A 蛋白
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) (Active) protein
PPM1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 1-382) protein (GST tag)PPM1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) protein (His tag)PPM1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by SDS-PAGE
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag)Crystallography grade PPM1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (AA 2-382) protein (His tag)Crystallography grade PPM1A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) (Transcript Variant 1) protein (His tag)PPM1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
- 别名
- Protein Phosphatase 1a,ppm1a (PPM1A 产品)
- 别名
- PP2C-ALPHA Protein, PP2CA Protein, PP2Calpha Protein, pp2ca1 Protein, ppp1r13b Protein, si:ch211-253p18.1 Protein, wu:fd42g12 Protein, zgc:153820 Protein, 2310003C21Rik Protein, 2900017D14Rik Protein, AI427932 Protein, AU017636 Protein, MMPa-2 Protein, MPPa-1 Protein, Pp2c1 Protein, pp2c-alpha Protein, pp2ca Protein, pp2calpha Protein, pp2ca2 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1A Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ab Protein, protein phosphatase 1A, magnesium dependent, alpha isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1A Protein, protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Aa Protein, PPM1A Protein, ppm1ab Protein, Ppm1a Protein, ppm1a.L Protein, ppm1aa Protein
- 背景
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
- 分子量
- 42.3 kDa
- NCBI登录号
- NP_066283
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