PRKAG1 Protein (Catalytic Subunit, Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all PRKAG1 蛋白
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- 蛋白类型
- Recombinant
- 产品特性
- Catalytic Subunit, Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PRKAG1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAG1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- Abstract
- PRKAG1 产品
- 别名
- MGC68503 Protein, zgc:63896 Protein, wu:fa94d09 Protein, wu:fd12h04 Protein, AMPKG Protein, Prkaac Protein, Prkga1 Protein, AA571379 Protein, BB036179 Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit Protein, protein kinase AMP-activated non-catalytic subunit gamma 1 Protein, prkag1.S Protein, prkag1 Protein, PRKAG1 Protein, Prkag1 Protein
- 背景
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- 分子量
- 28.1 kDa
- NCBI登录号
- NP_997626
- 途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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