PKC iota Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PKC iota (PRKCI) 蛋白
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PKC iota protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PRKCI protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKCI 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- 别名
- Prkci (PRKCI 产品)
- 别名
- DXS1179E Protein, PKCI Protein, nPKC-iota Protein, aPKC[l] Protein, hal Protein, has Protein, PRKCI Protein, PKC Protein, 2310021H13Rik Protein, AI427505 Protein, PKClambda Protein, Pkci Protein, Pkcl Protein, Prkcl Protein, aPKClambda Protein, mKIAA4165 Protein, protein kinase C iota Protein, protein kinase C, iota Protein, PRKCI Protein, prkci Protein, Prkci Protein
- 背景
- This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
- 分子量
- 68.1 kDa
- NCBI登录号
- NP_002731
- 途径
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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