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POGLUT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

POGLUT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2729296
发货至: 中国
  • 抗原 See all POGLUT1 蛋白
    POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 1
    • 1
    • 1
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This POGLUT1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human POGLUT1 / KTELC1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product POGLUT1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
    别名
    Poglut1,ktelc1 (POGLUT1 产品)
    别名
    C3orf9 Protein, CLP46 Protein, KDELCL1 Protein, KTELC1 Protein, MDSRP Protein, Rumi Protein, hCLP46 Protein, MDS010 Protein, 9630046K23Rik Protein, Ktelc1 Protein, protein O-glucosyltransferase 1 Protein, POGLUT1 Protein, Poglut1 Protein
    背景
    This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
    分子量
    46 kDa
    NCBI登录号
    NP_689518
    途径
    Notch Signaling
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